• Installation
  • Run CalicoST on a simulated data
  • Run CalicoST on prostate cancer dataset
  • Specification of running parameters of CalicoST
CalicoST
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Contents:

  • Run CalicoST on a simulated data
    • Download the data
    • Run CalicoST to infer CNAs and cancer clones assuming spots are purely tumor or purely normal
    • Load the results of CalicoST
  • Run CalicoST on prostate cancer dataset
    • Obtain the data
    • Compute allele counts by preprocessing: genotyping and reference-based phasing
    • Estimate tumor proportion per spot
      • Load and visualize inferred tumor proportions
    • Run CalicoST to infer CNAs and cancer clones based on estimated tumor proportions
      • Load CalicoST-generated result tables
      • Visualize CalicoST-generated plots
    • Reconstruct tumor phylogeny and phylogeography
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